Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM05TBE)

Drug Name

KLS-0611 Drug Info

Synonyms

Mucin stimulator (dry eye), Kissei

Indication

Disease Entry	ICD 11	Status	REF
Xerophthalmia	5B55.Y	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

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Drug(s) Targeting Mucin (MUC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
15(S)-hydroxyeicosatetraenoic acid (ophthalmic, dry eye), Alcon	DMUM3CP	Ocular disease	1F00.1Z	Discontinued in Phase 3	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT00721656) Phase 2 Study of KLS-0611 in Patients With Dry Eye Syndromes. U.S. National Institutes of Health.
2	WO patent application no. 2011,1034,23, Cyclobutane and methylcyclobutane derivatives as janus kinase inhibitors.
3	15(S)-hydroxyeicosatetraenoic acid (15-HETE), a product of arachidonic acid peroxidation, is an active component of hemozoin toxicity to monocytes. Parassitologia. 1999 Sep;41(1-3):199-202.