General Information of Drug (ID: DM08XS2)

Drug Name
ERIC-1 Drug Info
Synonyms UJ13A; NCAM antagonist, Imperial Cancer Research Technology; ERIC-1, ICRT; ERIC-1, Imperial CancerResearch Technology
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Terminated [1]
Cross-matching ID
TTD Drug ID
DM08XS2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
IMGN901 DMIUC3M Solid tumour/cancer 2A00-2F9Z Phase 2 [3]
FGLL DMY61GX Alzheimer disease 8A20 Phase 1 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neural cell adhesion molecule (NCAM) TTUBJQ3 NOUNIPROTAC Antagonist [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004519)
2 Monoclonal antibody UJ13A recognizes the neural cell adhesion molecule (NCAM). Int J Cancer. 1989 Dec 15;44(6):1062-8.
3 Lorvotuzumab mertansine, a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models. MAbs. 2014 Mar-Apr;6(2):556-66.
4 An NCAM mimetic, FGL, alters hippocampal cellular morphometry in young adult (4 month-old) rats. Neurochem Res. 2013 Jun;38(6):1208-18.