Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0JW2V)

Drug Name

APETX2 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Pain	MG30-MG3Z	Investigative	[1]

Therapeutic Class

Analgesics

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Acid-sensing ion channel 3 (ASIC3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
benzamil	DM57SVW	Discovery agent	N.A.	Investigative	[3]
agmatine	DMSBZ29	Discovery agent	N.A.	Investigative	[4]
A-317567	DMGWO9J	Discovery agent	N.A.	Investigative	[4]
THA-902	DMKCY0X	Fibromyalgia	MG30.01	Investigative	[4]
arcaine	DMXOYK0	Discovery agent	N.A.	Investigative	[4]
GMQ	DMM0ZKQ	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acid-sensing ion channel 3 (ASIC3)	TTLGDIS	ASIC3_HUMAN	Blocker	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4135).
2	Challenges in analgesic drug development. Clin Pharmacol Ther. 2009 Oct;86(4):447-50.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 684).
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 686).