Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0K6QH)

Drug Name

Bis-Napthyl Beta-Ketophosphonic Acid Drug Info

Synonyms

BIS-NAPTHYL BETA-KETOPHOSPHONIC ACID; [(1R)-1-naphthalen-1-yl-2-naphthalen-2-yl-2-oxoethyl]phosphonic acid; (2-NAPHTHALEN-2-YL-1-NAPHTHALEN-1-YL-2-OXO-ETHYL)-PHOSPHONIC ACID; KTP; 1kyn; AC1L9K5C; DB02360; (1R)-1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethylphosphonic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 446833
TTD Drug ID: DM0K6QH

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Cathepsin G (CTSG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
JNJ-10311795	DM7OTQS	Chronic obstructive pulmonary disease	CA22	Phase 2	[2]
Peptide analog 59	DMZAMNX	N. A.	N. A.	Patented	[3]
Peptide analog 61	DM45JMT	N. A.	N. A.	Patented	[3]
Peptide analog 55	DMVLP8H	N. A.	N. A.	Patented	[3]
Peptide analog 60	DMMSTNA	N. A.	N. A.	Patented	[3]
Peptide analog 70	DMN43Q5	N. A.	N. A.	Patented	[3]
Peptide analog 56	DMBCFJU	N. A.	N. A.	Patented	[3]
Peptide analog 57	DM6IQWE	N. A.	N. A.	Patented	[3]
Peptide analog 58	DM7X62M	N. A.	N. A.	Patented	[3]
Peptide analog 62	DM28NK0	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cathepsin G (CTSG)	TTQAJF1	CATG_HUMAN	Inhibitor	[1]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50(8):1727-30.
3	Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014).Expert Opin Ther Pat. 2015;25(10):1145-58.