Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0LK0V)

Drug Name

NGM438 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Aggressive cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Leukocyte-associated Ig-like receptor 1 (LAIR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NC410	DMZSIV1	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukocyte-associated Ig-like receptor 1 (LAIR1)	TTSI7A8	LAIR1_HUMAN	Antagonist	[2]

------------------------------------------------------------------------------------

References

1	ClinicalTrials.gov (NCT05311618) A Phase 1/1b Dose Escalation/Expansion Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of NGM Biopharma
3	Clinical pipeline report, company report or official report of NextCure.