Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0NPIO)

Drug Name

SSYA10-001 Drug Info

Synonyms

3-[(2-Nitrophenyl)sulfanylmethyl]-4-prop-2-enyl-1H-1,2,4-triazole-5-thione

Indication

Disease Entry	ICD 11	Status	REF
Coronavirus infection	1D92	Preclinical	[1]
Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[1]
Severe acute respiratory syndrome (SARS)	1D65	Preclinical	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

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Drug(s) Targeting MERS-CoV helicase (Hel)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID31955138-compound-16	DM9LS0R	Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[2]
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Drug(s) Targeting SARS-CoV helicase (Hel)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID21925774-compound-5e	DM94ZOI	Severe acute respiratory syndrome (SARS)	1D65	Preclinical	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
2	Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors. Acta Pharm. 2020 Jun 1;70(2):145-159.
3	2,6-Bis-arylmethyloxy-5-hydroxychromones With Antiviral Activity Against Both Hepatitis C Virus (HCV) and SARS-associated Coronavirus (SCV) Eur J Med Chem. 2011 Nov;46(11):5698-704.