Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0OYLQ)

Drug Name

I-vation Drug Info

Synonyms

Triamcinolone implant

Indication

Disease Entry	ICD 11	Status	REF
Diabetic retinopathy	9B71.0	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting Corticosteroid-binding globulin (SERPINA6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ciclesonide	DM2NA4K	Allergic rhinitis	CA08.0	Approved	[3]
Paramethasone	DM6PR40	Inflammation	1A00-CA43.1	Approved	[3]
Alclometasone	DMAE84F	Exanthem		Approved	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Corticosteroid-binding globulin (SERPINA6)	TTJL8VG	CBG_HUMAN	Modulator	[2]

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References

1	Drug delivery implants in the treatment of vitreous inflammation. Mediators Inflamm. 2013;2013:780634.
2	Cortisol binding in rat skeletal muscle. J Biol Chem. 1975 Feb 25;250(4):1207-11.
3	Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity. J Clin Endocrinol Metab. 2000 Jan;85(1):361-7.
4	The anti-inflammatory effects of LY178002 and LY256548. Agents Actions. 1989 Jun;27(3-4):300-2.