General Information of Drug (ID: DM16JFS)

Drug Name
(R)-2-(biphenyl-4-sulfonylamino)-propionic acid Drug Info
Synonyms SCHEMBL4651862; CHEMBL198184; BDBM24034; biphenylsulfonamide carboxylate, 11; (2R)-2-[(4-phenylbenzene)sulfonamido]propanoic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
24901481
TTD Drug ID
DM16JFS

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug(s) Targeting Aggrecanase-1 (ADAMTS4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
1607004-34-1 DMM2N4T N. A. N. A. Patented [2]
US9206139, 4 DM3NE8J N. A. N. A. Patented [2]
US9206139, 5 DMB4JS7 N. A. N. A. Patented [2]
SC-44463 DMBPNKT N. A. N. A. Terminated [3]
MMI270 DM38N2K Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aggrecanase-1 (ADAMTS4) TTYG6BU ATS4_HUMAN Inhibitor [1]

References

1 Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):311-6.
2 Aggrecanase inhibitors. US9206139.
3 Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50.