Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1B0PY)

Drug Name

CLP-635 Drug Info

Synonyms

CLP-656

Indication

Disease Entry	ICD 11	Status	REF
Epilepsy	8A60-8A68	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Solute carrier family 12 member 5 (SLC12A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DIOA	DMBKJL8	Discovery agent	N.A.	Investigative	[1]
VU0240551	DMU3YRH	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Solute carrier family 12 member 5 (SLC12A5)	TTH6UZY	S12A5_HUMAN	Modulator	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 972).
2	Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5383-8.