Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1FLXD)

Drug Name

CAN04 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin 1 receptor accessory protein (IL1RAP)	TTWS50K	IL1AP_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04452214) A Study of the Safety and Tolerance of CAN04 in Combination With Pembrolizumab in Subjects With Solid Tumors. U.S. National Institutes of Health.
2	A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors (CANFOUR)