Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM1H75D)

Drug Name

Z-100 Drug Info

Synonyms

Ancer; SSM; Specific Substance of Maruyama; Ancer 20

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting Interferon receptor (IFNR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
HDV-interferon	DMAX632	Hepatitis C virus infection	1E51.1	Phase 2	[3]
Bropirimine	DMMT1YQ	Virus infection	1A24-1D9Z	Discontinued in Phase 3	[4]
Omniferon	DMSKAGP	Solid tumour/cancer	2A00-2F9Z	Terminated	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT00016692) Safety and Tolerability of Z-100 in Patients With Early HIV Infection. U.S. National Institutes of Health.
2	Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. J Gen Virol. 2004 Sep;85(Pt 9):2603-13.
3	Interferon in HDV infection. Antiviral Res. 1994 Jul;24(2-3):165-74.
4	Comparison between circulating interferon and drug levels following administration of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP) to different animal species. J Interferon Res. 1982;2(3):317-27.
5	US patent application no. 2004,0229,936, Treatment of hepatitis c virus infection with sesquiterpene lactones.