Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM25VY8)

Drug Name

Mydicar Drug Info

Synonyms

Mydicar (TN)

Indication

Disease Entry	ICD 11	Status	REF
Heart failure	BD10-BD13	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gallopamil	DMXBR27	Asthma	CA23	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)	TTE6THL	AT2A2_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00534703) Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure and a Left Ventricular Assist Device. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Celladon.
3	Interaction of D-600 with the transmembrane domain of the sarcoplasmic reticulum Ca(2+)-ATPase. Am J Physiol Cell Physiol. 2000 Jul;279(1):C166-72.