General Information of Drug (ID: DM2DXHO)

Drug Name
Ro092210 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DM2DXHO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CI-1040 DMF3DZX Discovery agent N.A. Investigative [1]
U0126 DM31OGF Discovery agent N.A. Investigative [1]
LLZ16406 DMOGZLU Discovery agent N.A. Investigative [1]
Drug Name Drug ID Indication ICD 11 Highest Status REF
CI-1040 DMF3DZX Discovery agent N.A. Investigative [1]
URMC-099 DMCJXWK Discovery agent N.A. Investigative [2]
U0126 DM31OGF Discovery agent N.A. Investigative [1]
LLZ16407 DM783BP Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MAPK/ERK kinase kinase 1 (MAP3K1) TTQBCEJ M3K1_HUMAN Inhibitor [1]
MAPK/ERK kinase kinase 2 (MAP3K2) TTK1N5G M3K2_HUMAN Inhibitor [1]

References

1 Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci. 2002 Jan;23(1):40-5.
2 Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48.