Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2LBHN)

Drug Name
JTE-051 Drug Info
Indication
Disease Entry ICD 11 Status REF
Plaque psoriasis EA90.0 Phase 2 [1]
Allergy 4A80-4A85 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM2LBHN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting T-cell-specific kinase (ITK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CPI-818 DMMBQ20 T-cell lymphoma 2A90 Phase 1 [4]
Pyrazolo[4,3-c]pyridine derivative 2 DMCDFLQ N. A. N. A. Patented [5]
PMID27774824-Compound-Figure3Example7 DMXDOGK N. A. N. A. Patented [5]
BMS-509744 DMGH1LX Inflammation 1A00-CA43.1 Investigative [6]
BMS-488516 DM6Y1QF Inflammation 1A00-CA43.1 Investigative [6]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
T-cell-specific kinase (ITK) TT3C80U ITK_HUMAN Inhibitor [3]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035711)
3 Characterisation of a K390R ITK Kinase Dead Transgenic Mouse - Implications for ITK as a Therapeutic Target. PLoS One. 2014; 9(9): e107490.
4 Clinical pipeline report, company report or official report of Corvus Pharmaceuticals.
5 Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1.Expert Opin Ther Pat. 2017 Feb;27(2):127-143.
6 Treatment of depersonalization with serotonin reuptake blockers. J Clin Psychopharmacol. 1990 Jun;10(3):200-3.