Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2N8TW)

Drug Name

7alpha,25-dihydroxycholesterol Drug Info

Synonyms

7alpha-25-OHC

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting EBV-induced G-protein coupled receptor 2 (GPR183)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
27-hydroxycholesterol	DM2L6OZ	Discovery agent	N.A.	Investigative	[3]
25-hydroxycholesterol	DMCHAQ7	Discovery agent	N.A.	Investigative	[3]
7alpha,27-dihydroxycholesterol	DM52UOM	Discovery agent	N.A.	Investigative	[3]
7beta-hydroxycholesterol	DMPHJZU	Discovery agent	N.A.	Investigative	[3]
7beta, 27-dihydroxycholesterol	DMSDINR	Discovery agent	N.A.	Investigative	[3]
7alpha-hydroxycholesterol	DMH6LD0	Discovery agent	N.A.	Investigative	[3]
7beta, 25-dihydroxycholesterol	DMYKXWE	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
EBV-induced G-protein coupled receptor 2 (GPR183)	TTME5YJ	GP183_HUMAN	Agonist	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4350).
2	Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7.
3	Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23.