Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2NF6X)

Drug Name

MIV-210 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis B virus infection	1E51.0	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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Drug(s) Targeting Hepatitis B virus Reverse transcriptase (HBV RT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Entecavir	DM7VTQO	Hepatitis B virus infection	1E51.0	Approved	[3]
Clevudine	DMR21Q3	Hepatitis B	1E51	Phase 3	[4]
LB80380	DMJM9LZ	Hepatitis B virus infection	1E51.0	Phase 2b	[5]
Pradefovir	DM1O0DV	Hepatitis virus infection	1E50-1E51	Phase 2	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hepatitis B virus Reverse transcriptase (HBV RT)	TTS5K1M	DPOL_HBVA3	Modulator	[2]

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References

1	Clinical pipeline report, company report or official report of Medivir (2011).
2	Emerging antivirals for the treatment of hepatitis B
3	Effect of hepatitis B virus reverse transcriptase variations on entecavir treatment response. J Infect Dis. 2014 Sep 1;210(5):701-7.
4	2011 Pipeline of Bukwang.
5	2011 Pipeline of LG Life Sciences.
6	DOI: 10.1128/AAC.01566-05