Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2QIN1)

Drug Name

HT-100 Drug Info

Synonyms

Halofunginone

Indication

Disease Entry	ICD 11	Status	REF
Duchenne dystrophy	8C70	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bifunctional aminoacyl-tRNA synthetase (EPRS)	TTXYCDZ	SYEP_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT02525302) HT-100 Long-term Study in DMD Patients Who Completed HALO-DMD-02.
2	Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nat Chem Biol. 2012 Feb 12;8(3):311-7.