Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM324RM)

Drug Name

JCAR023 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Neuroblastoma	2D11.2	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Neural cell adhesion molecule L1 (L1CAM)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CD171 specific CAR T cells expressing EGFRt	DM2AHXW	Ganglioneuroblastoma	2A00.11	Phase 1	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Neural cell adhesion molecule L1 (L1CAM)	TTC9D3K	L1CAM_HUMAN	CAR-T-Cell-Therapy	[1]

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT02311621) Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01