Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM36R21)

Drug Name
US8481733, 95 Drug Info
Synonyms SCHEMBL4356213; SCHEMBL4356209; CHEMBL2325936; BDBM98283; US8481733, 95
Cross-matching ID
PubChem CID
57961044
TTD Drug ID
DM36R21

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Activated CDC42 kinase 1 (ACK-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BDBM50379214 DMPOVZ6 N. A. N. A. Patented [2]
US8481733, 106 DMV6FL8 N. A. N. A. Patented [1]
US8481733, 118 DMZQIKL N. A. N. A. Patented [1]
PMID17280833C30 DMXHS4L Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Activated CDC42 kinase 1 (ACK-1) TTIET93 ACK1_HUMAN Inhibitor [1]

References

1 Substituted imidazopyr- and imidazotri-azines. US8481733.
2 Kinase modulators for the treatment of cancer. US9416123.
3 Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and prelimin... Bioorg Med Chem Lett. 2007 Apr 15;17(8):2305-9.