Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM37R5F)

Drug Name

ISIS 29219 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting PDK-1 messenger RNA (PDK-1 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NU-6102	DMMOFKD	Discovery agent	N.A.	Investigative	[2]
(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one	DM27WDP	Discovery agent	N.A.	Investigative	[3]
BX-517	DMBQIEF	Discovery agent	N.A.	Investigative	[3]
ISIS 29475	DMEBQUN	Discovery agent	N.A.	Investigative	[1]
ISIS 29233	DMGV4O7	Discovery agent	N.A.	Investigative	[1]
ISIS 29471	DMG4RMZ	Discovery agent	N.A.	Investigative	[1]
ISIS 29470	DMPCK7Y	Discovery agent	N.A.	Investigative	[1]
ISIS 29477	DMKQMXV	Discovery agent	N.A.	Investigative	[1]
ISIS 29239	DMHQF1J	Discovery agent	N.A.	Investigative	[1]
SU-6689	DMDNA23	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	US patent application no. 6,124,272, Antisense modulation of PDK-1 expression.
2	Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1353-7.
3	Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8.