Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3G0OP)

Drug Name

CAR-T cells targeting CD34 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Acute myeloid leukaemia	2A60	Preclinical	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Hematopoietic progenitor cell antigen CD34 (CD34)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AMR-001	DMGE8FK	Heart failure	BD10-BD13	Phase 2	[2]
CART-34 cells	DMRNIB9	Acute myeloid leukaemia	2A60	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hematopoietic progenitor cell antigen CD34 (CD34)	TTZAVYN	CD34_HUMAN	CAR-T-Cell-Therapy	[1]

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References

1	ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia
2	National Cancer Institute Drug Dictionary (drug id 743421).
3	ClinicalTrials.gov (NCT03291444) CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS