Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3NE8J)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Aggrecanase-1 (ADAMTS4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1607004-34-1	DMM2N4T	N. A.	N. A.	Patented	[1]
US9206139, 5	DMB4JS7	N. A.	N. A.	Patented	[1]
SC-44463	DMBPNKT	N. A.	N. A.	Terminated	[2]
MMI270	DM38N2K	Discovery agent	N.A.	Investigative	[3]
(R)-2-(biphenyl-4-sulfonylamino)-propionic acid	DM16JFS	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Aggrecanase inhibitors. US9206139.
2	Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50.
3	Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):311-6.