Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3U58I)

Drug Name
Oxindole derivative 4 Drug Info
Synonyms PMID28117607-Compound-40
Cross-matching ID
TTD Drug ID
DM3U58I

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Leucine-rich repeat kinase 2 (LRRK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DNL151 DMZT89C Parkinson disease 8A00.0 Phase 1 [2]
DNL201 DMFEORD Parkinson disease 8A00.0 Phase 1 [2]
BIIB094 DMLUO5K Parkinson disease 8A00.0 Phase 1 [3]
Pyrrolo-pyridine derivative 2 DMVNY5I N. A. N. A. Patented [1]
Bidentate ligands of Markush derivative 2 DM2QNMC N. A. N. A. Patented [1]
Oxindole derivative 3 DM0ENF3 N. A. N. A. Patented [1]
Aminopyridine derivative 3 DMSLJE8 N. A. N. A. Patented [1]
Fused thiophene derivative 1 DMV7IX4 N. A. N. A. Patented [1]
Bidentate ligands of Markush derivative 1 DMB08D3 N. A. N. A. Patented [1]
Pyrrolo-pyrimidine derivative 8 DMZH27I N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Leucine-rich repeat kinase 2 G2019S mutant (LRRK2 G2019S)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pyrrolo-pyridine derivative 2 DMVNY5I N. A. N. A. Patented [1]
Oxindole derivative 3 DM0ENF3 N. A. N. A. Patented [1]
Aminopyridine derivative 3 DMSLJE8 N. A. N. A. Patented [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leucine-rich repeat kinase 2 (LRRK2) TTK0FEA LRRK2_HUMAN Inhibitor [1]
Leucine-rich repeat kinase 2 G2019S mutant (LRRK2 G2019S) TT6AXLY LRRK2_HUMAN Inhibitor [1]

References

1 Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-2016).Expert Opin Ther Pat. 2017 Jun;27(6):667-676.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of Ionis