Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3XC31)

Drug Name
AMG 104 Drug Info
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM3XC31

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Thymic stromal lymphopoietin (TSLP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tezepelumab DM9R5J6 Severe asthma CA23 Approved [2]
A378 DMUWRTB Asthma CA23 IND submitted [3]
MEDI9929 DMGD1YP Asthma CA23 Phase 2 [4]
CSJ117 DMZJUV6 Asthma CA23 Phase 2 [5]
AZD8630 DMMUF0O Asthma CA23 Phase 1 [6]
PF-07275315 DMHRVUY Atopic dermatitis EA80 Phase 1 [7]
SAR443765 DMLYI4Z Asthma CA23 Phase 1 [8]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thymic stromal lymphopoietin (TSLP) TTHMW3T TSLP_HUMAN Not Available [1]

References

1 Clinical pipeline report, company report or official report of Amgen
2 Tezepelumab in Adults with Uncontrolled Asthma. N Engl J Med. 2017 Sep 7;377(10):936-946.
3 Clinical pipeline report, company report or official report of Klus Pharma
4 Human immunoglobulin G2Lambda monoclonal antibody directed against thymic stromal lymphopoietin (MEDI9929). European medicines agency science medicines health (EMEA-001613-PIP01-14). European Union. 2015.
5 TSLP Inhibitors for Asthma: Current Status and Future Prospects. Drugs. 2020 Apr;80(5):449-458.
6 Clinical pipeline report, company report or official report of AstraZeneca
7 Clinical pipeline report, company report or official report of Pfizer
8 Clinical pipeline report, company report or official report of Sanofi