Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3YGWL)

• Drug Name: Alpha-Methylisocitric Acid Drug Info
• Synonyms: alpha-methylisocitric acid; methylisocitrate; 71183-66-9; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid; Methylisocitric acid; (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate; AC1NUSCP; SCHEMBL1533821; CHEBI:15607; ZINC902108; LMFA01050444; AKOS030526883; DB04072; HY-16581; C04593; 3-carboxy-2,3-dideoxy-4-C-methyl-L-threo-pentaric acid; UNII-8518EC1Z2E component HHKPKXCSHMJWCF-WVBDSBKLSA-N; UNII-ZC5YS92LCE component HHKPKXCSHMJWCF-WVBDSBKLSA-N

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5459784
  ChEBI ID: CHEBI:15607
  CAS Number: CAS 71183-66-9
  TTD Drug ID: DM3YGWL

Molecule-Related Drug Atlas

Drug(s) Targeting Citrate hydro-lyase (ACO2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aconitate Ion	DMJ5U8C	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-Aconitate Ion	DMT8L5R	Discovery agent	N.A.	Investigative	[1]
Tricarballylic Acid	DMLKWTG	Discovery agent	N.A.	Investigative	[1]
Isocitric Acid	DMJKW4S	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Citrate hydro-lyase (ACO2)	TTMTF2P	ACON_HUMAN	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.