General Information of Drug (ID: DM4AI91)

Drug Name
Endo-CD Drug Info
Synonyms Endostatin-cytosine deaminase fusion protein
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DM4AI91

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Endostatin (COL18A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RetinoStat DMVXZJ4 Macular degeneration 9B78.3 Phase 2 [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Endostatin (COL18A1) TT63DI9 COIA1_HUMAN Modulator [1]

References

1 Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.Mol Cancer Ther.2011 Aug;10(8):1327-36.
2 Safety and biodistribution of an equine infectious anemia virus-based gene therapy, RetinoStat( ), for age-related macular degeneration. Hum Gene Ther. 2012 Sep;23(9):980-91.