Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4FHQR)

Drug Name

Canfosfamide Drug Info

Synonyms

Telcyta (TN)

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Glutathione S-transferase P (GSTP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ezatiostat	DM2L9CO	Myelodysplastic syndrome	2A37	Phase 2	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glutathione S-transferase P (GSTP1)	TT40K12	GSTP1_HUMAN	Modulator	[1]

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References

1	Mechanism of glutathione transferase P1-1-catalyzed activation of the prodrug canfosfamide (TLK286, TELCYTA). Biochemistry. 2013 Nov 12;52(45):8069-78.
2	National Cancer Institute Drug Dictionary (drug id 485244).