Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM592YS)

Drug Name

2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide Drug Info

Synonyms

2,3,5,6-TETRAFLUORO-4-METHOXY-BENZAMIDE; 2,3,5,6-tetrafluoro-4-methoxybenzamide; C8H5F4NO2; BEK; AC1LCVZS; SCHEMBL1002032; ZINC12501151; AKOS000299242

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 657081
TTD Drug ID: DM592YS

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Galectin-3 (LGALS3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GR-MD-02	DM9QF65	Hypertension	BA00-BA04	Phase 2	[2]
GB0139	DMA8KQR	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[3]
GB0139	DMA8KQR	Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[4]
PFFFFF	DM9AZKE	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Galectin-3 (LGALS3)	TTFPQV7	LEG3_HUMAN	Inhibitor	[1]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	Therapy of experimental NASH and fibrosis with galectin inhibitors. PLoS One. 2013 Dec 18;8(12):e83481.
3	An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE). Am J Respir Crit Care Med. 2023 Jan 15;207(2):138-149.
4	Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation. Front Pharmacol. 2022 Aug 8;13:949264.
5	Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries. Bioorg Med Chem Lett. 2007 Feb 1;17(3):793-8.