General Information of Drug (ID: DM5GAOZ)

Drug Name
2-(2-(phenylamino)pyrimidin-4-ylamino)benzamide Drug Info
Synonyms 4-anilinopyrimidine 2a; CHEMBL428213; BDBM15995
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
23647253
TTD Drug ID
DM5GAOZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NKP-1339 DM5AWK1 Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
PMID25991433-Compound-A1 DM89LF0 N. A. N. A. Patented [3]
PMID25991433-Compound-F2 DM37VIQ N. A. N. A. Patented [3]
7-azaindole derivative 1 DMQL5B7 N. A. N. A. Patented [3]
7-azaindole derivative 5 DMV3H98 N. A. N. A. Patented [3]
PMID25991433-Compound-P6 DMNDVC9 N. A. N. A. Patented [3]
PMID25991433-Compound-J3 DM17P3F N. A. N. A. Patented [3]
PMID25991433-Compound-P1 DMD8AX6 N. A. N. A. Patented [3]
PMID25991433-Compound-O3 DMVOWS5 N. A. N. A. Patented [3]
PMID25991433-Compound-L1 DM2135Y N. A. N. A. Patented [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Stress-activated protein kinase JNK1 (JNK1) TT0K6EO MK08_HUMAN Inhibitor [1]

References

1 Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1496).
3 c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Expert Opin Ther Pat. 2015;25(8):849-72.