Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5P0PC)

Drug Name
PF-07248144 Drug Info
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM5P0PC

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone acetyltransferase KAT6A (KAT6A) TT6O1J0 KAT6A_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04606446) A Phase 1 Dose Escalation and Expansion Study to Evaluate Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, and Anti-tumor Activity of PF-07248144 in Participants With Advanced or Metastatic Solid Tumors. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Pfzer