Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5T4IS)

Drug Name

VP-102 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Molluscum contagiosum infection	1E76	Phase 3	[1]
Common wart	1E80	Phase 2	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Serine/threonine PP2A-alpha (PPP2CA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LB-100	DMC04SR	Astrocytoma	2A00.0Y	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein phosphatase 1A (PPM1A)	TTLA7IX	PPM1A_HUMAN	Inhibitor	[2]
Serine/threonine PP2A-alpha (PPP2CA)	TTHTKNY	PP2AA_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT03377803) Cantharidin Application in Molluscum Patients (CAMP-2). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Inhibition of protein phosphatase 2A enhances cytotoxicity and accessibility of chemotherapeutic drugs to hepatocellular carcinomas. Mol Cancer Ther. 2014 Aug;13(8):2062-72.