Details of the Drug-Related molecule(s) Interaction Atlas | DrugMAP

General Information of Drug (ID: DM5WYJ6)

Drug Name	Thiamine pyrophosphate Drug Info
Synonyms	B-Neurox; Berolase; Biosyth; Bioxylasi; Bivitasi; Co-Bi; Co-carboxylase; Cocarbina; Cocarboxil; Cocarboxilasa; Cocarboxylasum; Cocarboxylasum [INN-Latin]; Coenbione; Coxylase; Diphosphothiamin; Diphosphothiamine; Farmaneurina; Metabolase; Nutrase; Pyrolase; Pyruvodehydrase; TDP (thiamin ester); TPP (coenzyme); Thiamine pyrophosphate; Thiamine pyrophosphate chloride; Thiamine pyrophosphoric ester; Thiamine-PP; Thiaminediphosphate; Thiaminepyrophosphate; Thiaminpyrophosphate; UNII-XMK8K8EVIU; cocarboxylase
Cross-matching ID	PubChem CID 9068 ChEBI ID ChEBI:18290 CAS Number CAS 154-87-0 TTD Drug ID DM5WYJ6 VARIDT Drug ID DR00335

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Mitochondrial thiamine pyrophosphate carrier (SLC25A19)	DTT82QK	TPC_HUMAN	Substrate	[1]
Solute carrier family 35 member E4 (SLC35E4)	DT9V8W1	S35E4_HUMAN	Substrate	[2]

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References

1	Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15927-32.
2	The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.7.9.11)