Details of the Drug-Related molecule(s) Interaction Atlas

Benzamide derivative 19 Drug Info

PMID25470667-Compound-Figure5-14

Cross-matching ID

PubChem CID

53242014

TTD Drug ID

DM5YNTM

General Information of Drug (ID: DM5YNTM)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Diacylglycerol acyltransferase 1 (DGAT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hesperetin	DMKER83	High blood cholesterol level	5C80.00	Approved	[2]
LCQ908	DMFLJHQ	Familial chylomicronemia syndrome	5C80	Phase 3	[3]
AZD7687	DMS9I6A	Diabetic complication	5A2Y	Phase 1	[4]
P-7435	DMNZQU5	Diabetic complication	5A2Y	Phase 1	[5]
PMID25470667-Compound-Figure4-1A	DMMVQW8	N. A.	N. A.	Patented	[1]
Azole derivative 7	DMVUJGI	N. A.	N. A.	Patented	[1]
Carbamide derivative 3	DM4ISCQ	N. A.	N. A.	Patented	[1]
T863	DMX41ZF	Discovery agent	N.A.	Patented	[1]
Lactam derivative 5	DMX5FYZ	N. A.	N. A.	Patented	[1]
Pyridine-carboximide derivative 2	DMHXWZB	N. A.	N. A.	Patented	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Diacylglycerol acyltransferase 1 (DGAT1)	TTF8P9I	DGAT1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58.
2	In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens. Planta Med. 2004 Mar;70(3):258-60.
3	DGAT1 inhibitors as anti-obesity and anti-diabetic agents. Curr Opin Drug Discov Devel. 2010 Jul;13(4):489-96.
4	Clinical pipeline report, company report or official report of AstraZeneca (2011).
5	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033014)