Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM648KQ)

Drug Name

ALN-FLU01 Drug Info

Synonyms

RNAi therapeutic (influenza), Alnylam/Novartis; NP/NA gene-silencing siRNA (influenza infection), Alnylam/Novartis

Indication

Disease Entry	ICD 11	Status	REF
Influenza virus infection	1E30-1E32	Preclinical	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Influenza NA messenger RNA (Influenza NA mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 3308	DMSIBWP	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Influenza NA messenger RNA (Influenza NA mRNA)	TTM27B5	NRAM_I97A1	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022658)
2	Respiratory viral diseases: access to RNA interference therapy. Drug Discov Today Ther Strateg. 2007; 4(4): 273-276.
3	US patent application no. 5,580,767, Inhibition of influenza viruses by antisense oligonucleotides.