General Information of Drug (ID: DM6A9UR)

Drug Name
Flavonoid derivative 7 Drug Info
Synonyms PMID26161698-Compound-6
Cross-matching ID
PubChem CID
74978523
TTD Drug ID
DM6A9UR

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Preclinical Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
KENPAULLONE DMAGVXW Discovery agent N.A. Patented [2]
Roscovitine derivative 1 DMD1G3Z N. A. N. A. Patented [1]
Tricyclic benzimidazole derivative 1 DM5SD9E N. A. N. A. Patented [1]
4-(thiazol-5-yl)-pyrimidine derivative 2 DMMQFCN N. A. N. A. Patented [1]
Pyrazolo[1,5-a]-1,3,5-triazine derivative 1 DMOK7CW N. A. N. A. Patented [1]
Naphthyridine and isoquinoline derivative 1 DMTGIP7 N. A. N. A. Patented [1]
PMID26161698-Compound-18 DM6JVR5 N. A. N. A. Patented [1]
L-751250 DMOERXK Obesity 5B81 Preclinical [3]
Olomoucine DMNAFG1 N. A. N. A. Terminated [3]
aloisine A DM5U1LN Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase 5 (CDK5) TTL4Q97 CDK5_HUMAN Inhibitor [1]

References

1 Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
2 1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3 beta. Bioorg Med Chem Lett. 2004 Jan 19;14(2):413-6.
3 Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.
4 Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003 Jan 16;46(2):222-36.