Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6ONY7)

Drug Name

Ac-Phe-D-Thr(PO3H2)-Pip-Nal-Gln-NH2 Drug Info

Synonyms

CHEMBL436759; Ac-Phe-D-Thr(PO3H2)-Pip-Nal-Gln-NH2

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Rotamase Pin1 (PIN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Avastin+/-Tarceva	DMA86FL	Non-small-cell lung cancer	2C25.Y	Phase 3	[2]
Beta-(2-Naphthyl)-Alanine	DMP21ZO	Discovery agent	N.A.	Investigative	[3]
(R,)-2-(2-naphthamido)-5-phenylpent-4-enoic acid	DMCW5A9	Discovery agent	N.A.	Investigative	[4]
(R)-2-(2-naphthamido)-3-p-tolylpropanoic acid	DMXGCYZ	Discovery agent	N.A.	Investigative	[4]
3,6,9,12,15,18-HEXAOXAICOSANE	DMY26JI	Discovery agent	N.A.	Investigative	[3]
(R)-3-(2-naphthamido)-4-m-tolylbutanoic acid	DM5TH2W	Discovery agent	N.A.	Investigative	[4]
(R)-2-(2-naphthamido)-3-m-tolylpropanoic acid	DMVEMNA	Discovery agent	N.A.	Investigative	[4]
(R)-2-(2-naphthamido)-5-phenylpent-4-ynoic acid	DM9WL6O	Discovery agent	N.A.	Investigative	[4]
Ac-Phe-Thr(PO3H2)-Pip-Nal-Gln-NH2	DMSWTPX	Discovery agent	N.A.	Investigative	[1]
Ac-Bth-Thr(PO3H2)-Pip-Nal-Gln-NH2	DMSE29N	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries. J Med Chem. 2006 Apr 6;49(7):2147-50.
2	Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma.PLoS One. 2016 Jun 3;11(6):e0156833.
3	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4	Structure-based design of novel human Pin1 inhibitors (II). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2210-4.