Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6P91T)

Drug Name
INGN-241 Drug Info
Synonyms AD-IL-24, Introgen; AD-mda-7, Introgen; Adenovirus-IL-24, Introgen; Adenovirus-mda-7, Introgen
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM6P91T

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-24 (IL24) TT1EPXZ IL24_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT00116363) Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma. U.S. National Institutes of Health.
2 Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients. Mol Ther. 2005 Jan;11(1):160-72.