Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6WX1A)

Drug Name

CCX-662 Drug Info

Synonyms

CCX-733; CCX-754; CXCR7 antagonists, ChemoCentryx

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Preclinical Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting C-X-C chemokine receptor type 7 (ACKR3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GW-766994	DMKC0J5	Asthma	CA23	Discontinued in Phase 2	[2]
JT07	DMHBWOP	Solid tumour/cancer	2A00-2F9Z	Preclinical	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-X-C chemokine receptor type 7 (ACKR3)	TTRQJTC	ACKR3_HUMAN	Antagonist	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 80).
2	Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial. Clin Exp Allergy. 2014 Apr;44(4):508-16.
3	Clinical pipeline report, company report or official report of Jyant Technologies.