Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6X430)

Drug Name
SJA-6017 Drug Info
Synonyms
Calpain Inhibitor VI; SJA-6017; SJA6017; N-(4-Fluorophenylsulfonyl)-L-Valyl-L-Leucinal; CHEMBL288365; SCHEMBL1907361; ZINC1544687; BDBM50114340; J-012283; (S)-2-(4-fluorophenylsulfonamido)-3-methyl-N-((S)-4-methyl-1-oxopentan-2-yl)butanamide; (S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-formyl-3-methyl-butyl)-3-methyl-butyramide
Cross-matching ID
PubChem CID
9885817
CAS Number
CAS 190274-53-4
TTD Drug ID
DM6X430

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Calpain-2 (CAPN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABT-957 DMB9N4J Alzheimer disease 8A20 Phase 1 [2]
PMID25399719-Compound-17 DMRXKJZ N. A. N. A. Patented [3]
Epoxysuccinate derivative 9 DM49FU0 N. A. N. A. Patented [3]
Epoxysuccinate derivative 4 DMCF6M8 N. A. N. A. Patented [3]
Carboxamide derivative 7 DM8TQS4 N. A. N. A. Patented [3]
Epoxysuccinate derivative 7 DMTSPVF N. A. N. A. Patented [3]
Carboxamide derivative 10 DM5WMO9 N. A. N. A. Patented [3]
Carboxamide derivative 11 DM1DN94 N. A. N. A. Patented [3]
Carboxamide derivative 8 DM6HI34 N. A. N. A. Patented [3]
Epoxysuccinate derivative 10 DMYF39U N. A. N. A. Patented [3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calpain-2 (CAPN2) TTG5QB7 CAN2_HUMAN Inhibitor [1]

References

1 Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors. Bioorg Med Chem. 2008 Jul 15;16(14):6911-23.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.