Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM783BP)

Drug Name
LLZ16407 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DM783BP

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting MAPK/ERK kinase kinase 2 (MAP3K2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CI-1040 DMF3DZX Discovery agent N.A. Investigative [1]
URMC-099 DMCJXWK Discovery agent N.A. Investigative [2]
U0126 DM31OGF Discovery agent N.A. Investigative [1]
Ro092210 DM2DXHO Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MAPK/ERK kinase kinase 2 (MAP3K2) TTK1N5G M3K2_HUMAN Inhibitor [1]

References

1 Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci. 2002 Jan;23(1):40-5.
2 Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. J Med Chem. 2013 Oct 24;56(20):8032-48.