Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7EVQX)

Drug Name

ISIS 32003 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting PI3K p110 beta messenger RNA (PIK3CB mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LY-292223	DML36ZE	Discovery agent	N.A.	Investigative	[2]
Ethyl 1-[(1H-benzimidazol-2(3H)one-5-yl)sulfonyl]-1H-pyrrole-2-carboxylate	DM3FH02	Discovery agent	N.A.	Investigative	[2]
3-(4-morpholinothieno[3,2-d]pyrimidin-2-yl)phenol	DM54MDH	Discovery agent	N.A.	Investigative	[3]
ISIS 32014	DMF5SK8	Discovery agent	N.A.	Investigative	[1]
ISIS 32024	DMPKGIU	Discovery agent	N.A.	Investigative	[1]
ISIS 32035	DM47B2O	Discovery agent	N.A.	Investigative	[1]
ISIS 32000	DM0O9WM	Discovery agent	N.A.	Investigative	[1]
ISIS 32021	DMISB5V	Discovery agent	N.A.	Investigative	[1]
ISIS 32028	DMATWDO	Discovery agent	N.A.	Investigative	[1]
ISIS 32039	DMY1R0Q	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
PI3K p110 beta messenger RNA (PIK3CB mRNA)	TT9H4P3	PK3CB_HUMAN	Not Available	[1]

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References

1	US patent application no. 6,133,032, Antisense modulation of PI3 kinase p110 beta expression.
2	LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family. Bioorg Med Chem Lett. 2001 Apr 9;11(7):909-13.
3	Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors. Bioorg Med Chem. 2007 Sep 1;15(17):5837-44.