Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7I2AC)

Drug Name

mRNA-3745 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Glycogen storage disease type IA	5C51.3	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucose-6-phosphatase catalytic subunit 1 messenger RNA (G6PC1 mRNA)	TTL5KSF	G6PC1_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT05095727) A Phase 1/2, Adaptive, Open-label, Single Ascending Dose to Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-3745 in Participants With Glycogen Storage Disease Type 1a (GSD1a), Followed by an Open-label Extension. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Moderna