General Information of Drug (ID: DM7NXMB)

Drug Name
[HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL Drug Info
Synonyms [HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL; SB-485345; 2ai7; 2ai8; AC1NRD35; DB08523
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5289329
TTD Drug ID
DM7NXMB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GSK1322322 DM1EPMF Bacterial infection 1A00-1C4Z Phase 2 [2]
Actinonin DMT4P89 N. A. N. A. Terminated [3]
Formic Acid DMNFZC6 Discovery agent N.A. Investigative [4]
Double Oxidized Cysteine DM6TU84 Discovery agent N.A. Investigative [4]
Cysteinesulfonic Acid DMXI8FP Discovery agent N.A. Investigative [4]
3-Sulfinoalanine DMILTRN N. A. N. A. Investigative [4]
HYDROXY[3-(6-METHYLPYRIDIN-2-YL)PROPYL]FORMAMIDE DMA4SIN Discovery agent N.A. Investigative [1]
2-(3-BENZOYLPHENOXY)ETHYL(HYDROXY)FORMAMIDE DMWMFTJ Discovery agent N.A. Investigative [1]
VRC3375 DM1QKVL Discovery agent N.A. Investigative [5]
N-alkyl urea hydroxamic acids DM9T0OK Discovery agent N.A. Investigative [6]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Staphylococcus Peptide deformylase (Stap-coc def) TTICO5G DEF_STAAU Inhibitor [1]

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2 Peptide deformylase: a new target in antibacterial, antimalarial and anticancer drug discovery. Curr Med Chem. 2015;22(2):214-36.
3 Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry. 2000 Feb 15;39(6):1256-62.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach. Antimicrob Agents Chemother. 2004 Jan;48(1):250-61.
6 N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity. Antimicrob Agents Chemother. 2002 Sep;46(9):2752-64.