General Information of Drug (ID: DM7VG8L)

Drug Name
MTC-896 Drug Info
Synonyms MC-5 antagonists (dermatological disease), Mimetica
Indication
Disease Entry ICD 11 Status REF
Seborrhea ED91.2 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM7VG8L

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
JNJ-10229570 DMY7Q3I Acne vulgaris ED80 Phase 2 [3]
MT-II DMKT1DA Female sexual arousal dysfunction HA01.1 Investigative [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanocortin receptor 5 (MC5R) TT6QAJ3 MC5R_HUMAN Antagonist [2]

References

1 ClinicalTrials.gov (NCT02395549) A Study to Determine the Efficacy of Topically Applied MTC896 Gel in Subjects With Acne Vulgaris. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Avarx.
3 A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids. J Dermatol Sci. 2011 Jul;63(1):23-32.
4 The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. Eur J Pharmacol. 2002 Apr 12;440(2-3):141-57.