Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7WGXS)

Drug Name

FR-76830 Drug Info

Synonyms

113243-75-7; FR 76830; 3-Pyridinecarboxamide,2-methyl-N-[2-(4-morpholinyl)ethyl]-4-(3-nitrophenyl)-6-phenyl-; FR-76830; HNBRMVZTOLAZRW-UHFFFAOYSA-N; ACMC-20mhoq; AC1MIZ8R; SCHEMBL9601411; fr76830; CTK4A8167; DTXSID70150329; 2-Methyl-N-(2-(4-morpholinyl)ethyl)-4-(3-nitrophenyl)-6-phenylnicotinamide; AKOS030543198; 2-Methyl-N-(4-morpholinylethyl)-4-(3-nitrophenyl)-6-phenyl-3-pyridinecarboxamide; 3-(2-morpholinoethylcarbamoyl)-2-methyl-4-(3-nitrophenyl)-6-phenylpyridine

Indication

Disease Entry	ICD 11	Status	REF
Angina pectoris	BA40	Terminated	[1]

Cross-matching ID

PubChem CID: 3082657
CAS Number: CAS 113243-75-7
TTD Drug ID: DM7WGXS

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting ATP phosphatase (ATPase)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LYC-30937	DMP05GL	Plaque psoriasis	EA90.0	Phase 2	[3]
BY-1949	DM8ZFS3	Cognitive impairment	6D71	Discontinued in Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ATP phosphatase (ATPase)	TT5WKM8	NOUNIPROTAC	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002286)
2	On the mode of cardioprotection produced by a new bradycardic agent, FR 76830, during ischaemia and after reperfusion in the isolated perfused rat heart: a 31P-NMR study. Cardiovasc Res. 1990 Dec;24(12):1008-12.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	An activation of synaptosomal Na+,K(+)-ATPase by a novel dibenzoxazepine derivative (BY-1949) in the rat brain: its functional role in the neurotransmitter uptake systems. J Neurochem. 1992 Jan;58(1):362-8.