Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7WYCM)

Drug Name

6-aza-uridine monophosphate Drug Info

Synonyms

6-Aza-ump; 6-Azauridine-5'-monophosphate; 6-aza uridine 5'-monophosphate; 1los; UP6; [(2R,3S,4R,5R)-5-(3,5-dioxo-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; aza UMP; 6-Azauridine-5'-phosphate; 6-Azauridine 5'M; NSC47549; 6-Azauridine 5'MP; 6-azauridine 5'-phosphate; AC1L45DF; 6-aza-uridine monophosphate; C6-Uridine Derivative, 18; 6-Azauridine-5-monophosphate; CHEMBL463480; SCHEMBL3214622; BDBM21340; 6-Azauridine 5'-phosphoric acid; ZINC12503861; AKOS027381721; DB03718; W-201761

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 150959
ChEBI ID: CHEBI:46319
CAS Number: CAS 2018-19-1
TTD Drug ID: DM7WYCM

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Mycobacterium Orotidine phosphate decarboxylase (MycB pyrF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Uridine-5'-Monophosphate	DMG1NM7	Discovery agent	N.A.	Investigative	[2]
6-Hydroxyuridine-5'-Phosphate	DMDMNQV	Discovery agent	N.A.	Investigative	[2]
Xanthosine-5'-monophosphate disodium salt	DM1GJX8	Discovery agent	N.A.	Investigative	[3]
6-amino-uridine monophosphate	DMUZOYN	Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mycobacterium Orotidine phosphate decarboxylase (MycB pyrF)	TTV7Y40	PYRF_MYCTO	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics. J Med Chem. 2006 Aug 10;49(16):4937-45.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase. J Med Chem. 2008 Feb 14;51(3):432-8.