Details of the Drug-Related molecule(s) Interaction Atlas

US9567304, Compound F-54 Drug Info

SCHEMBL16529160; ASAFNJMZLYOBFG-OAHLLOKOSA-N; BDBM286586; US9567304, Compound F-54; 7-[[(3R)-3-aminopiperidin-1-yl]methyl]-8-chloro-3-[(5-chloro-2-ethylsulfonylphenyl)methyl]-6-(trifluoromethyl)-1H-quinazoline-2,4-dione; 7-((R)-3-Amino-piperidin-1-ylmethyl)-8-chloro-3-(5-chloro-2-ethanesulfonyl-benzyl)-6-trifluoromethyl-1H-quinazoline-2,4-dione

Cross-matching ID

PubChem CID

72195492

TTD Drug ID

DM81MV6

General Information of Drug (ID: DM81MV6)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Epithelial discoidin domain receptor 1 (DDR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9567304, Compound N-9	DMCGUNB	N. A.	N. A.	Patented	[1]
US9156852, 83	DM1K5T0	N. A.	N. A.	Patented	[2]
US9695118, 8	DMAD3VL	N. A.	N. A.	Patented	[3]
NG7	DMW1PL7	N. A.	N. A.	Patented	[4]
VAPBGCRAUJRZPO-UHFFFAOYSA-N	DMOVEZF	N. A.	N. A.	Patented	[3]
BDBM50080408	DM4I829	N. A.	N. A.	Patented	[1]
US9695118, 4	DMZF3AQ	N. A.	N. A.	Patented	[3]
PMID23521020C7k	DMPCTED	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Epithelial discoidin domain receptor 1 (DDR1)	TTI1FPZ	DDR1_HUMAN	Inhibitor	[1]

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References

1	Quinazolinedione derivative. US9567304.
2	Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases. US9156852.
3	Benzamide derivative. US9695118.
4	Fused 2-aminothiazole compounds. US8765747.
5	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors. J Med Chem. 2013 Apr 25;56(8):3281-95.