Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM84D9W)

• Drug Name: 8-Amino-1,3-Dimethyl-3,7-Dihydropurine-2,6-Dione Drug Info
• Synonyms: 8-Aminotheophylline; 8-Aminoteofiliny; Theophylline, 8-amino-; 19410-53-8; 8-Aminoteofiliny [Polish]; 8-AMINO-1,3-DIMETHYL-3,7-DIHYDROPURINE-2,6-DIONE; 1H-Purine-2,6-dione, 8-amino-3,7-dihydro-1,3-dimethyl-; 8-Amino-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-amino-1,3-dimethyl-7H-purine-2,6-dione; 8-amino-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione; 8-amino-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; 8-Aminotheophyline; 1rs2; AC1L3TFO; AC1Q6LC1; Oprea1_659892; Oprea1_298061; Oprea1_442990; CHEMBL298737

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 95034
  CAS Number: CAS 19410-53-8
  TTD Drug ID: DM84D9W

Molecule-Related Drug Atlas

Drug(s) Targeting Bacterial Dihydroneopterinaldolase (Bact folB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bropirimine	DMMT1YQ	Virus infection	1A24-1D9Z	Discontinued in Phase 3	[1]
7,8-dihydrobiopterin	DMQU4XM	Discovery agent	N.A.	Investigative	[1]
6-Hydroxymethyl-7,8-Dihydropterin	DMYF60K	Discovery agent	N.A.	Investigative	[1]
7,8-Dihydroneopterin	DM5TXY1	Discovery agent	N.A.	Investigative	[1]
9-Methylguanine	DM54FRI	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Dihydroneopterinaldolase (Bact folB)	TTG9CFY	FOLB_ECOLI	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.