Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM87XVD)

Drug Name
ET140202 Drug Info
Indication
Disease Entry ICD 11 Status REF
Hepatocellular carcinoma 2C12.02 Phase 1 [1]
Liver cancer 2C12 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM87XVD

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Alpha-fetoprotein (AFP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MM-093 DMXJWNS Autoimmune diabetes 5A10 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Alpha-fetoprotein (AFP) TTCFEA1 FETA_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT03998033) An Open-Label, Dose Escalation, Multi-Center Phase I/II Research Trial to Assess the Safety of ET140202 T Cells and Determine the Recommended Phase II Dose ("RP2D") in Adults With Advanced Hepatocellular Carcinoma ("HCC"). U.S.National Institutes of Health.
2 ClinicalTrials.gov (NCT03965546) Clinical Study of ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Advanced Liver Cancer. U.S.National Institutes of Health.
3 MM-093, a recombinant human alpha-fetoprotein for the potential treatment of rheumatoid arthritis and other autoimmune diseases. Curr Opin Mol Ther. 2007 Dec;9(6):603-10.