General Information of Drug (ID: DM8BLYO)

Drug Name
RO320-2947/001 Drug Info
Synonyms RO320-2947/001; GTPL791; SCHEMBL1223391
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10255622
TTD Drug ID
DM8BLYO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ASM8 DMTHR4U Allergic asthma CA23.0 Phase 2 [3]
banyu (I) DM9JXIZ Discovery agent N.A. Investigative [4]
RO116-9132/238 DM6XM1D Discovery agent N.A. Investigative [2]
RO116-4875/608 DMFTW0U Discovery agent N.A. Investigative [2]
RO330-0802/001 DMGOPY1 Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CCR3 messenger RNA (CCR3 mRNA) TTU3Y87 CCR3_HUMAN Antagonist [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 791).
2 Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002 Jun 15;165(12):1602-9.
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 60).
4 Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002 Dec 5;456(1-3):1-10.